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Regenerative Therapies for Erectile Dysfunction


Dimitris Hatzichristou

Professor of Urology
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Content: The treatment of organically induced erectile dysfunction has mostly focused on managing the symptoms (with PDE5i) rather than treating the dysfunction. However, it seems that we are moving into a new era, that of regenerative therapies. Today there is increased clinical interest in employing regenerative therapies, including low-intensity extracorporeal shockwave therapy (Li-ESWT), platelet rich plasma (PRP), and stem cell therapy (SCT), in the treatment of ED. But still, clinicians are often confused as to what they can expect from these treatments. Dimitris Hatzichristou is a Professor of Urology and with his team they have been studying regenerative treatments for about 10 years. Specifically, with his team, they implemented many studies trying to find which is the best way to apply shock wave therapy and what kind of improvement one could expect. In addition, recently, he published the only randomized placebo-controlled study in order to assess the efficacy of PRP treatment for ED. These treatments are very frequently used in clinical practice, but not always in ways that conform with the available data. Triggered by two very recent publications*, Dimitris Hatzichristou shares key knowledge that stems from some of the most well conducted research studies. As professionals and patients often require a good understanding of what these treatments can do, this talk provides distilled information about why regenerative therapies are a game changer, what the most important clinical findings are and also how this knowledge applies to clinical practice.


*Poulios E, Mykoniatis I, Pyrgidis N, Zilotis F, Kapoteli P, Kotsiris D, Kalyvianakis D, Hatzichristou D. Platelet-Rich Plasma (PRP) Improves Erectile Function: A Double-Blind, Randomized, Placebo-Controlled Clinical Trial. J Sex Med. 2021 May;18(5):926-935.


Produced in 2022

Dimitris Hatzichristou

Professor of Urology

Dimitris Hatzichristou, MD, PhD, FECSM, is Professor of Urology of Aristotle University of Thessaloniki, Greece. He is also President of the Institute for the Study of Urological Diseases (ISUD), a non profit organization, dedicated to education and awareness on Urological conditions.


He received his MD and Ph.D. degrees and completed his training in Urology at Aristotle University in Thessaloniki, Greece. Then, he completed a 2-year fellowship in Andrology at Boston University, Boston, USA and then he worked as visiting scholar (prostate diseases) for a year at Stanford University, California, USA. Prof. Hatzichristou organized and chaired the foundation meeting of the European Society for Sexual Medicine in 1995, served as Secretary General (1995-97), President Elect (1999-2001) and President (2001-2004) of ESSM. He has been also a faculty member of the European School of Urology (ESU), founding member of the European Society of Andrological Urology (ESAU), member of the Executive Committee of the International Society for Sexual Medicine (ISSM), the EAU Committee for the guidelines on erectile dysfunction (2004-2014) and co-chairman of the Committee on “Diagnostics and Scales in Sexual Medicine” of the International Consultation in Sexual Medicine since 2004. Dr Hatzichristou has served as Review and Educational Editor for the Journal of Sexual Medicine and the Journal for Impotence Research, Editorial board member for Urologia Internationalis and the Journal for Sexual and Reproductive Medicine, and reviewer in major scientific journals, including European Urology, Journal of Urology, International British Journal of Urology. He has been invited speaker in more than 250 international meetings and teaching courses worldwide. He has authored 25 book chapters in international books, as well as more than 120 review and peer-review papers with more than 15000 citations (h-factor=51).

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